Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

Summary: Gene expression studies suggest that aging of the human brain is determined by a complex interplay of molecular events, although both its region- and cell-type-specific consequences remain poorly understood. Here, we extensively characterized aging-altered gene expression changes across ten...

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Bibliographic Details
Main Authors: Lilach Soreq, Jamie Rose, Eyal Soreq, John Hardy, Daniah Trabzuni, Mark R. Cookson, Colin Smith, Mina Ryten, Rickie Patani, Jernej Ule
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716316849