Lack of evidence of seronegative infection in an endemic area of Chagas disease

Lack of evidence of seronegative infection in an endemic area of Chagas disease

ABSTRACT The diagnosis of Chagas disease is based on the detection of Trypanosoma cruzi (T. cruzi)-specific antibodies. Nonetheless, there is concern about the sensitivity of current serological assays due to reports of T. cruzi PCR positivity among seronegative individuals. The aim of this study wa...

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Bibliographic Details
Main Authors: Léa Campos de Oliveira, Tzong-Hae Lee, Ariela Mota Ferreira, Ana Luiza Bierrenbach, Marcela de Souza-Basqueira, Cláudia Di Lorenzo Oliveira, Clareci Silva Cardoso, Carlos Henrique Valente Moreira, Marcio K. Oikawa, Antonio Luiz P. Ribeiro, Michael P Busch, Ester Cerdeira Sabino
Format: Article
Language:English
Published: Universidade de São Paulo 2019-02-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Chagas disease
Diagnosis
Infectious diseases
Prevention and control
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652019005000602&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652019005000602&lng=en&tlng=en

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