DAP12 overexpression induces osteopenia and impaired early hematopoiesis.

DAP12 overexpression induces osteopenia and impaired early hematopoiesis.

ITAM-bearing transmembrane signaling adaptors such as DAP12 and FcRγ are important players in bone homeostasis, but their precise role and functions are still unknown. It has been shown that osteoclast differentiation results from the integration of the RANK and of the DAP12 and FcRγ signaling pathw...

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Bibliographic Details
Main Authors: Geneviève Despars, Subramanya N M Pandruvada, Adrienne Anginot, Chantal Domenget, Pierre Jurdic, Marlène Mazzorana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679081?pdf=render

Internet

http://europepmc.org/articles/PMC3679081?pdf=render

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