Decontamination of digital image sensors and assessment of electron microscope performance in a BSL-3 containment
A unique biological safety level (BSL)-3 cryo-electron microscopy facility with a 200 keV high-end cryo-electron microscope has been commissioned at the University of Texas Medical Branch (UTMB) to study the structure of viruses and bacteria classified as select agents. We developed a microscope dec...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-05-01
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Series: | AIMS Biophysics |
Subjects: | |
Online Access: | http://www.aimspress.com/biophysics/article/285/fulltext.html |
Summary: | A unique biological safety level (BSL)-3 cryo-electron microscopy facility with a 200 keV high-end cryo-electron microscope has been commissioned at the University of Texas Medical Branch (UTMB) to study the structure of viruses and bacteria classified as select agents. We developed a microscope decontamination protocol based on chlorine dioxide gas with a continuous flow system. In this paper we report on testing digital camera sensors (both CCD and CMOS direct detector) in a BSL-3 environment, and microscope performance after chlorine dioxide (ClO<sub>2</sub>) decontamination cycles. |
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ISSN: | 2377-9098 |