Activation of a helper and not regulatory human CD4+ T cell response by oncolytic H-1 parvovirus.

Activation of a helper and not regulatory human CD4+ T cell response by oncolytic H-1 parvovirus.

BACKGROUND:H-1 parvovirus (H-1 PV), a rodent autonomous oncolytic parvovirus, has emerged as a novel class of promising anticancer agents, because of its ability to selectively find and destroy malignant cells. However, to probe H-1 PV multimodal antitumor potential one of the major prerequisites is...

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Bibliographic Details
Main Authors: Olivier Moralès, Audrey Richard, Nathalie Martin, Dhafer Mrizak, Magalie Sénéchal, Céline Miroux, Véronique Pancré, Jean Rommelaere, Perrine Caillet-Fauquet, Yvan de Launoit, Nadira Delhem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281136?pdf=render

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http://europepmc.org/articles/PMC3281136?pdf=render

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