Haplotype estimation from fuzzy genotypes using penalized likelihood.

The Composite Link Model is a generalization of the generalized linear model in which expected values of observed counts are constructed as a sum of generalized linear components. When combined with penalized likelihood, it provides a powerful and elegant way to estimate haplotype probabilities from...

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Bibliographic Details
Main Authors: Hae-Won Uh, Paul H C Eilers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169573?pdf=render