Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness.

Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness.

<h4>Background</h4>The ambiguous role of transcription factor Sp3 for tumour progression is still debated since it was described as a transcriptional repressor or activator. Here we tried to decipher the molecular mechanisms implicated in Sp3 accumulation observed in aggressive tumours.&...

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Main Authors: Khadija Essafi-Benkhadir, Sébastien Grosso, Alexandre Puissant, Guillaume Robert, Makram Essafi, Marcel Deckert, Emmanuel Chamorey, Olivier Dassonville, Gérard Milano, Patrick Auberger, Gilles Pagès
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19212434/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19212434/pdf/?tool=EBI

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