Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization

Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization

Cellular cross-talk within the tumor microenvironment (TME) by exosomes is known to promote tumor progression. Tumor promoting macrophages with an M2 phenotype are suppressors of anti-tumor immunity. However, the impact of tumor-derived exosomes in modulating macrophage polarization in the lung TME...

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Bibliographic Details
Main Authors: Alexandra Pritchard, Sultan Tousif, Yong Wang, Kenneth Hough, Saad Khan, John Strenkowski, Balu K. Chacko, Victor M. Darley-Usmar, Jessy S. Deshane
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
exosomes
macrophage polarization
M2 macrophages
myeloid-derived suppressor cells
tumor associated macrophages
lung cancer
Online Access:https://www.mdpi.com/2073-4409/9/5/1303

Internet

https://www.mdpi.com/2073-4409/9/5/1303

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