Knowledge-based repositioning of the anti-HCV direct antiviral agent Sofosbuvir as SARS-CoV-2 treatment

Abstract The new human coronavirus named SARS-CoV-2 is a positive-sense RNA virus for which no specific drugs are currently available. A knowledge-based analysis strongly suggests a possible repositioning of the anti-HCV direct antiviral agent (DAA) Sofosbuvir as treatment for SARS-CoV-2. Indeed, th...

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Bibliographic Details
Main Authors: Luigi Buonaguro, Franco M. Buonaguro
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Infectious Agents and Cancer
Online Access:http://link.springer.com/article/10.1186/s13027-020-00302-x