Folded or Not? Tracking Bet v 1 Conformation in Recombinant Allergen Preparations.

Folded or Not? Tracking Bet v 1 Conformation in Recombinant Allergen Preparations.

Recombinant Bet v 1a (rBet v 1a) has been used in allergy research for more than three decades, including clinical application of so-called hypoallergens. Quantitative IgE binding to rBet v 1a depends on its native protein conformation, which might be compromised upon heterologous expression, purifi...

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Bibliographic Details
Main Authors: Felix Husslik, Kay-Martin Hanschmann, Ariane Krämer, Christian Seutter von Loetzen, Kristian Schweimer, Iris Bellinghausen, Regina Treudler, Jan C Simon, Lothar Vogel, Elke Völker, Stefanie Randow, Andreas Reuter, Paul Rösch, Stefan Vieths, Thomas Holzhauser, Dirk Schiller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4506129?pdf=render

Internet

http://europepmc.org/articles/PMC4506129?pdf=render

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