Oligomeric α-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease

Oligomeric α-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease

Blood-based biomarkers are needed to be used as easy, reproducible, and non-invasive tools for the diagnosis and prognosis of chronic neurodegenerative disorders including Parkinson's Disease (PD). In PD, aggregated toxic forms of α-Synuclein (α-Syn) accumulate within neurons in the brain and c...

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Bibliographic Details
Main Authors: Cristina Agliardi, Mario Meloni, Franca Rosa Guerini, Milena Zanzottera, Elisabetta Bolognesi, Francesca Baglio, Mario Clerici
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Oligomeric α-Synuclein
SNARE complex
Extravescicle
Neural derived exosome
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304605

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