Paclitaxel-Based Chemotherapy Targeting Cancer Stem Cells from Mono- to Combination Therapy

Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism that disrupts the dynamics of microtubules and induces mitotic arrest and cell death. Simultaneously, other mechanisms have...

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Bibliographic Details
Main Authors: Hend M. Nawara, Said M. Afify, Ghmkin Hassan, Maram H. Zahra, Akimasa Seno, Masaharu Seno
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/5/500