Rumex dentatus Inhibits Cell Proliferation, Arrests Cell Cycle, and Induces Apoptosis in MDA-MB-231 Cells through Suppression of the NF-κB Pathway

Rumex dentatus Inhibits Cell Proliferation, Arrests Cell Cycle, and Induces Apoptosis in MDA-MB-231 Cells through Suppression of the NF-κB Pathway

Background:Rumex dentatus, commonly known as tooth docked, is widely used in traditional system of medicines. Although it is well reported for its biological activities and medicinal value, only few studies have been carried out to assess its anticancer potential.Purpose: This study seeks to evaluat...

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Bibliographic Details
Main Authors: Riffat Batool, Ejaz Aziz, Benny K.-H. Tan, Tariq Mahmood
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Pharmacology
Subjects:
breast cancer
apoptosis
NF-κB
phosphorylation
Rumex dentatus
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00731/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00731/full

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