Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.

Agents promoting oligodendrocyte precursor cell differentiation have the potential to restore halted and/or delayed remyelination in patients with multiple sclerosis. However, few therapeutic targets have been identified. The objective of this study was to identify novel targets for promotion of rem...

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Bibliographic Details
Main Authors: Yongfeng Chen, Wei Zhen, Tony Guo, Yonggang Zhao, Ailian Liu, Justin P Rubio, David Krull, Jill C Richardson, Hongtao Lu, Ryan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5734789?pdf=render