Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome.

The standard 26S proteasome is responsible for the majority of myofibrillar protein degradation leading to muscle atrophy. The immunoproteasome is an inducible form of the proteasome. While its function has been linked to conditions of atrophy, its contribution to muscle proteolysis remains unclear....

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Bibliographic Details
Main Authors: Haiming M Liu, Deborah A Ferrington, Cory W Baumann, LaDora V Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5119786?pdf=render