A polyphenol, pyrogallol changes the acidic pH of the digestive vacuole of Plasmodium falciparum
Pyrogallol has a capability of generating free radicals like other antimalarial drugs such as artemisinin, which is thought to inhibit the proton pump located in the membrane of the Plasmodium falciparum digestive vacuole, thus alkalinising this acidic organelle. This study aimed to determine pH cha...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Biome Scientia
2021-08-01
|
Series: | Life Sciences, Medicine and Biomedicine |
Subjects: | |
Online Access: | http://biomescientia.com/index.php/lsmb/article/view/82 |