A polyphenol, pyrogallol changes the acidic pH of the digestive vacuole of Plasmodium falciparum

Pyrogallol has a capability of generating free radicals like other antimalarial drugs such as artemisinin, which is thought to inhibit the proton pump located in the membrane of the Plasmodium falciparum digestive vacuole, thus alkalinising this acidic organelle. This study aimed to determine pH cha...

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Bibliographic Details
Main Authors: Nur Saidatul Aqilah Ja’afar, Nik Nor Imam Nik Mat Zin, Fatin Sofia Mohamad, Nurhidanatasha Abu-Bakar
Format: Article
Language:English
Published: Biome Scientia 2021-08-01
Series:Life Sciences, Medicine and Biomedicine
Subjects:
Online Access:http://biomescientia.com/index.php/lsmb/article/view/82