Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation

Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation

The glycosphingolipid, α-galactosylceramide (αGalCer), when presented by CD1d on antigen-presenting cells, efficiently activates invariant natural killer T (iNKT) cells. Thereby, it modulates immune responses against tumors, microbial and viral infections, and autoimmune diseases. Recently, the prod...

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Bibliographic Details
Main Authors: Johanna von Gerichten, Dominic Lamprecht, Lukáš Opálka, Daphnée Soulard, Christian Marsching, Robert Pilz, Valentin Sencio, Silke Herzer, Bruno Galy, Viola Nordström, Carsten Hopf, Hermann-Josef Gröne, François Trottein, Roger Sandhoff
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Lipid Research
Subjects:
glycolipids
sphingolipids
mass spectrometry
immunology
bacteria
invariant natural killer T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322872

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http://www.sciencedirect.com/science/article/pii/S0022227520322872

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