LC/MS analysis and deep sequencing reveal the accurate RNA composition in the HIV-1 virion

Abstract The mechanism of action of various viruses has been the primary focus of many studies. Yet, the data on RNA modifications in any type of virus are scarce. Methods for the sensitive analysis of RNA modifications have been developed only recently and they have not been applied to viruses. In...

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Bibliographic Details
Main Authors: Anna Šimonová, Barbora Svojanovská, Jana Trylčová, Martin Hubálek, Ondřej Moravčík, Martin Zavřel, Marcela Pávová, Jan Hodek, Jan Weber, Josef Cvačka, Jan Pačes, Hana Cahová
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-45079-1