A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children.

A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children.

The emergence of drug resistant typhoid fever is a major public health problem, especially in Asia. An oral single dose typhoid vaccine would have major advantages. M01ZH09 is a live oral single dose candidate typhoid vaccine containing Salmonella enterica serovar Typhi (Ty2 aroC(-)ssaV(-)) ZH9 with...

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Bibliographic Details
Main Authors: Tinh Hien Tran, Thi Dung Nguyen, Thanh Truong Nguyen, Thi Thanh Van Ninh, Nguyen Bich Chau Tran, Van Minh Hoang Nguyen, Thi Thu Nga Tran, Thu Thuy Cao, Van Minh Pham, Thi Cam Binh Nguyen, Thi Diem Ha Tran, Van Toi Pham, Song Diep To, James I Campbell, Elaine Stockwell, Constance Schultsz, Cameron P Simmons, Clare Glover, Winnie Lam, Filipe Marques, James P May, Anthony Upton, Ronald Budhram, Gordon Dougan, Jeremy Farrar, Van Vinh Chau Nguyen, Christiane Dolecek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909895?pdf=render

Internet

http://europepmc.org/articles/PMC2909895?pdf=render

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