Effects of Long-Term In Vivo Exposure to Di-2-Ethylhexylphthalate on Thyroid Hormones and the TSH/TSHR Signaling Pathways in Wistar Rats

Effects of Long-Term In Vivo Exposure to Di-2-Ethylhexylphthalate on Thyroid Hormones and the TSH/TSHR Signaling Pathways in Wistar Rats

Di-(2-ethylhexyl)phthalate (DEHP) was a widely used chemical with human toxicity. Recent in vivo and in vitro studies suggested that DEHP-exposure may be associated with altered serum thyroid hormones (THs) levels, but the underlying molecular mechanisms were largely unknown. To explore the possible...

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Bibliographic Details
Main Authors: Xinwen Dong, Jin Dong, Yue Zhao, Jipeng Guo, Zhanju Wang, Mingqi Liu, Yunbo Zhang, Xiaolin Na
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:International Journal of Environmental Research and Public Health
Subjects:
DEHP
hypothalamus-pituitary-thyroid axis
TSH/TSHR
signaling pathways
molecular mechanisms
thyroid function
Online Access:http://www.mdpi.com/1660-4601/14/1/44

Internet

http://www.mdpi.com/1660-4601/14/1/44

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