IL-23 supports host defense against systemic Candida albicans infection by ensuring myeloid cell survival.

The opportunistic fungal pathogen Candida albicans can cause invasive infections in susceptible hosts and the innate immune system, in particular myeloid cell-mediated immunity, is critical for rapid immune protection and host survival during systemic candidiasis. Using a mouse model of the human di...

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Bibliographic Details
Main Authors: Selim Nur, Florian Sparber, Christina Lemberg, Eva Guiducci, Tiziano A Schweizer, Pascale Zwicky, Burkhard Becher, Salomé LeibundGut-Landmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008115