Host Defense Peptides as Templates for Antifungal Drug Development

Host Defense Peptides as Templates for Antifungal Drug Development

Current treatment for invasive fungal diseases is limited to three classes of antifungal drugs: azoles, polyenes, and echinocandins. The most recently introduced antifungal class, the echinocandins, was first approved nearly 30 years ago. The limited antifungal drug portfolio is rapidly losing its c...

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Bibliographic Details
Main Authors: Virginia Basso, Dat Q. Tran, André J. Ouellette, Michael E. Selsted
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Fungi
Subjects:
antifungals
host defense peptides
peptidomimetics
immunomodulation
multidrug resistance
defensins
Online Access:https://www.mdpi.com/2309-608X/6/4/241

Internet

https://www.mdpi.com/2309-608X/6/4/241

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