The ER quality control and ER associated degradation machineries are vital for viral pathogenesis
The endoplasmic reticulum (ER) is central to protein production and membrane lipid synthesis. The unfolded protein response (UPR) supports cellular metabolism by ensuring protein quality control in the ER. Most positive strand RNA viruses cause extensive remodeling of membranes and require active...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-03-01
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Series: | Frontiers in Plant Science |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00066/full |