Autoencoder-based detection of the residues involved in G protein-coupled receptor signaling

Abstract Regulator binding and mutations alter protein dynamics. The transmission of the signal of these alterations to distant sites through protein motion results in changes in protein expression and cell function. The detection of residues involved in signal transmission contributes to an elucida...

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Bibliographic Details
Main Authors: Yuko Tsuchiya, Kei Taneishi, Yasushige Yonezawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99019-z