Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of <i>Aspergillus fumigatus</i>

Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of <i>Aspergillus fumigatus</i>

<i>Aspergillus fumigatus</i> is an opportunistic human pathogen mainly infecting immunocompromised patients. The aim of this study was to characterize the role of arginine biosynthesis in virulence of <i>A. fumigatus</i> via genetic inactivation of two key arginine biosynthet...

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Bibliographic Details
Main Authors: Anna-Maria Dietl, Ulrike Binder, Ingo Bauer, Yana Shadkchan, Nir Osherov, Hubertus Haas
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
<i>Aspergillus fumigatus</i>
virulence
arginine
ornithine
siderophores
Online Access:https://www.mdpi.com/2073-4425/11/4/423

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