HMGB1 siRNA can reduce damage to retinal cells induced by high glucose in vitro and in vivo

HMGB1 siRNA can reduce damage to retinal cells induced by high glucose in vitro and in vivo

Shuang Jiang, Xiaolong Chen Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang, China Background: Diabetic retinopathy (DR), one of the most common complications of late-phase diabetes, is associated with many risk factors, among which continuous low-grade inflam...

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Bibliographic Details
Main Authors: Jiang S, Chen X
Format: Article
Language:English
Published: Dove Medical Press 2017-03-01
Series:Drug Design, Development and Therapy
Subjects:
Diabetic retinopathy
Small interfering RNA
Human Retinal endothelial cells
High-mobility group box-1
Inhibitor of nuclear factor kappa-β
Nuclear factor κB
Online Access:https://www.dovepress.com/hmgb1-sirna-can-reduce-damage-to-retinal-cells-induced-by-high-glucose-peer-reviewed-article-DDDT

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https://www.dovepress.com/hmgb1-sirna-can-reduce-damage-to-retinal-cells-induced-by-high-glucose-peer-reviewed-article-DDDT

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