Extracellular Vesicles Derived from Primary Adipose Stromal Cells Induce Elastin and Collagen Deposition by Smooth Muscle Cells within 3D Fibrin Gel Culture

Extracellular Vesicles Derived from Primary Adipose Stromal Cells Induce Elastin and Collagen Deposition by Smooth Muscle Cells within 3D Fibrin Gel Culture

Macromolecular components of the vascular extracellular matrix (ECM), particularly elastic fibers and collagen fibers, are critical for the proper physiological function of arteries. When the unique biomechanical combination of these fibers is disrupted, or in the ultimate extreme where fibers are c...

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Bibliographic Details
Main Authors: Eoghan M. Cunnane, Aneesh K. Ramaswamy, Katherine L. Lorentz, David A. Vorp, Justin S. Weinbaum
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Bioengineering
Subjects:
aneurysm
fibers
modulus
vasculature
regenerative medicine
Online Access:https://www.mdpi.com/2306-5354/8/5/51

Internet

https://www.mdpi.com/2306-5354/8/5/51

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