Phenotypic Variability Correlates with Clinical Outcome in Cryptococcus Isolates Obtained from Botswanan HIV/AIDS Patients

Phenotypic Variability Correlates with Clinical Outcome in Cryptococcus Isolates Obtained from Botswanan HIV/AIDS Patients

Cryptococcosis results in hundreds of thousands of deaths annually, predominantly in sub-Saharan Africa. Cryptococcus is an encapsulated yeast, and during infection, cells have the capacity for substantial morphological changes, including capsule enlargement and shedding and variations in cell shape...

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Bibliographic Details
Main Authors: Kenya E. Fernandes, Adam Brockway, Miriam Haverkamp, Christina A. Cuomo, Floris van Ogtrop, John R. Perfect, Dee A. Carter
Format: Article
Language:English
Published: American Society for Microbiology 2018-10-01
Series:mBio
Subjects:
Cryptococcus
capsule
cell size
meningitis
pleomorphism
yeasts
Online Access:https://doi.org/10.1128/mBio.02016-18

Internet

https://doi.org/10.1128/mBio.02016-18

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