Arsenic trioxide induces apoptosis and the formation of reactive oxygen species in rat glioma cells

Abstract Background Arsenic trioxide (As2O3) has a dramatic therapeutic effect on acute promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells. This study investigated whether As2O3 has an antitumor effect on glioma and explored the underlying mechanism. Results MT...

Full description

Bibliographic Details
Main Authors: Yuanyuan Sun, Chen Wang, Ligang Wang, Zhibo Dai, Kongbin Yang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11658-018-0074-4