The Effect of Depression on Health-Related Quality of Life Is Mediated by Fatigue in Persons with Multiple Sclerosis

The Effect of Depression on Health-Related Quality of Life Is Mediated by Fatigue in Persons with Multiple Sclerosis

The interrelations between fatigue, depression and health-related quality of life (HRQoL) in persons with multiple sclerosis (PwMS) are complex, and the directionality of the effects is unclear. To address this gap, the current study used a longitudinal design to assess direct and indirect effects o...

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Bibliographic Details
Main Authors: Stephanie Rodgers, Zina-Mary Manjaly, Pasquale Calabrese, Nina Steinemann, Marco Kaufmann, Anke Salmen, Andrew Chan, Jürg Kesselring, Christian P. Kamm, Jens Kuhle, Chiara Zecca, Claudio Gobbi, Viktor von Wyl, Vladeta Ajdacic-Gross
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Brain Sciences
Subjects:
multiple sclerosis
quality of life
depression
fatigue
longitudinal
Online Access:https://www.mdpi.com/2076-3425/11/6/751

Internet

https://www.mdpi.com/2076-3425/11/6/751

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