Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model.

AIMS: Enhancement of collateral development in coronary or peripheral artery disease is a therapeutic target, but it has proven difficult to achieve. Macrophages are key players in collateral remodeling, yet the effect of different macrophage subsets on arteriogenesis has not been investigated. METH...

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Bibliographic Details
Main Authors: Nadine Jetten, Marjo M P C Donners, Allard Wagenaar, Jack P M Cleutjens, Nico van Rooijen, Menno P J de Winther, Mark J Post
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3722193?pdf=render