An analysis of genetic diversity and inbreeding in Wuchereria bancrofti: implications for the spread and detection of drug resistance.

Estimates of genetic diversity in helminth infections of humans often have to rely on genotyping (immature) parasite transmission stages instead of adult worms. Here we analyse the results of one such study investigating a single polymorphic locus (a change at position 200 of the beta-tubulin gene)...

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Bibliographic Details
Main Authors: Thomas S Churcher, Anne E Schwab, Roger K Prichard, María-Gloria Basáñez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2275205?pdf=render