Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair

Abstract Bone-forming osteoblasts and -resorbing osteoclasts control bone injury repair, and myeloid-derived cells such as monocytes and macrophages are known to influence their behavior. However, precisely how these multiple cell types coordinate and regulate each other over time within the bone ma...

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Bibliographic Details
Main Authors: Chen Hao Lo, Etienne Baratchart, David Basanta, Conor C. Lynch
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84888-1