Photodegradation of trimeprazine triggered by self-photogenerated singlet molecular oxygen

The antihistaminic drug trimeprazine (1, also known as alimemazine) is photolabile under UV-A light in aerobic conditions. Irradiation of a methanol solution of trimeprazine produces two photoproducts which were isolated as N,N2-trimethyl-3-(10H-phenothiazin-10-yl sulfoxide) propan-1-amine (2) and N...

Full description

Bibliographic Details
Main Authors: Waseem Ahmad, Mohd. Rehan Zaheer, Anamika Gupta, Jawaid Iqbal
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312001251