Sterile protection against malaria is independent of immune responses to the circumsporozoite protein.

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein.

Research aimed at developing vaccines against infectious diseases generally seeks to induce robust immune responses to immunodominant antigens. This approach has led to a number of efficient bacterial and viral vaccines, but it has yet to do so for parasitic pathogens. For malaria, a disease of glob...

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Bibliographic Details
Main Authors: Anne Charlotte Grüner, Marjorie Mauduit, Rita Tewari, Jackeline F Romero, Nadya Depinay, Michèle Kayibanda, Eliette Lallemand, Jean-Marc Chavatte, Andrea Crisanti, Photini Sinnis, Dominique Mazier, Giampietro Corradin, Georges Snounou, Laurent Rénia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2147056?pdf=render

Internet

http://europepmc.org/articles/PMC2147056?pdf=render

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