Determination of Mother Centriole Maturation in CPAP-Depleted Cells Using the Ninein Antibody

BackgroundMutations in centrosomal protein genes have been identified in a number of genetic diseases in brain development, including microcephaly. Centrosomal P4.1-associated protein (CPAP) is one of the causal genes implicated in primary microcephaly. We previously proposed that CPAP is essential...

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Bibliographic Details
Main Authors: Miseon Lee, Kunsoo Rhee
Format: Article
Language:English
Published: Academya Publishing Co. 2015-03-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-53.pdf