Overexpression of piRNA pathway genes in epithelial ovarian cancer.

Overexpression of piRNA pathway genes in epithelial ovarian cancer.

The importance of the Piwi-interacting RNA (piRNA) pathway for germ cell maintenance, genome integrity, DNA methylation and retrotransposon control raises possible roles of this pathway in cancer. Indeed aberrant expression of human PIWI orthologs and Maelstrom has been observed in various cancers....

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Bibliographic Details
Main Authors: Shu Ly Lim, Carmela Ricciardelli, Martin K Oehler, Izza M D De Arao Tan, Darryl Russell, Frank Grützner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4059699?pdf=render

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