On the importance of polar interactions for complexes containing intrinsically disordered proteins.

There is a growing recognition for the importance of proteins with large intrinsically disordered (ID) segments in cell signaling and regulation. ID segments in these proteins often harbor regions that mediate molecular recognition. Coupled folding and binding of the recognition regions has been pro...

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Bibliographic Details
Main Authors: Eric T C Wong, Dokyun Na, Jörg Gsponer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3749945?pdf=render