The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells

The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells

PIX proteins activate the small GTPases Rac and Cdc42, and are known to have numerous functions in a variety of cell types. Using a genetic screen in C. elegans, the authors find that PIX-1 is required for the assembly or stability of integrin adhesion complexes between muscle cells.

Bibliographic Details
Main Authors: Jasmine C. Moody, Hiroshi Qadota, April R. Reedy, C. Denise Okafor, Niveda Shanmugan, Yohei Matsunaga, Courtney J. Christian, Eric A. Ortlund, Guy M. Benian
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18852-4

Internet

https://doi.org/10.1038/s41467-020-18852-4

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