8-Oxo-9-Dihydromakomakine Isolated from <i>Aristotelia chilensis</i> Induces Vasodilation in Rat Aorta: Role of the Extracellular Calcium Influx

8-Oxo-9-Dihydromakomakine Isolated from <i>Aristotelia chilensis</i> Induces Vasodilation in Rat Aorta: Role of the Extracellular Calcium Influx

8-Oxo-9-dihydromakomakine is a tetracyclic indole alkaloid extracted from leaves of the Chilean tree <i>Aristotelia chilensis</i>. The present study investigated the effects of this alkaloid on vascular response in tissues isolated from aortic segments obtained from normotensive rats. Ou...

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Bibliographic Details
Main Authors: Fredi Cifuentes, Javier Palacios, Adrián Paredes, Chukwuemeka R. Nwokocha, Cristian Paz
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
<i>Aristotelia chilensis</i> Molina Stuntz
vascular activity
endothelium-independent
indole alkaloid
8-oxo-9-dihydromakomakine
voltage-dependent calcium channels
Online Access:https://www.mdpi.com/1420-3049/23/11/3050

Internet

https://www.mdpi.com/1420-3049/23/11/3050

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