Human Immunodeficiency Virus (HIV) Infection and Use of Illicit Substances Promote Secretion of Semen Exosomes that Enhance Monocyte Adhesion and Induce Actin Reorganization and Chemotactic Migration

Human Immunodeficiency Virus (HIV) Infection and Use of Illicit Substances Promote Secretion of Semen Exosomes that Enhance Monocyte Adhesion and Induce Actin Reorganization and Chemotactic Migration

Semen exosomes (SE) from HIV-uninfected (HIV−) individuals potently inhibit HIV infection in vitro. However, morphological changes in target cells in response to SE have not been characterized or have the effect of HIV infection or the use of illicit substances, specifically psychostimulan...

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Bibliographic Details
Main Authors: Yuan Lyu, Hussein Kaddour, Steven Kopcho, Tyler D. Panzner, Nadia Shouman, Eun-Young Kim, Jeremy Martinson, Heather McKay, Otoniel Martinez-Maza, Joseph B. Margolick, Jack T. Stapleton, Chioma M. Okeoma
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
semen exosomes
monocytes
actin reorganization
psychostimulants
chemotaxis
morphometrics
Online Access:https://www.mdpi.com/2073-4409/8/9/1027

Internet

https://www.mdpi.com/2073-4409/8/9/1027

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