Expression, Purification and Functional Assessment of Smallest Isoform of Human Interleukin-24 in Escherichia coli

ABSTRACT Interleukin-24 (IL-24) is a novel tumor-suppressor gene that has different alternative splice isoforms. It has been shown that new smallest isoform of human IL-24 gene, lacking three exons, induces higher levels of cytotoxicity than all the isoforms, indicating shortest isoform of IL-24 may...

Full description

Bibliographic Details
Main Authors: Samira Valiyari, Reza Mahdian, Mona Salami, Mana Oloomi, Maryam Golshani, Mohammad Ali Shokrgozar, Saeid Bouzari
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2017-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100307&lng=en&tlng=en