TGF-β1/Smad signaling pathway regulates epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: in vitro and clinical analyses of cell lines and nomadic Kazakh patients from northwest Xinjiang, China.

Invasion and metastasis are the major causes of death in patients with esophageal squamous cell carcinoma (ESCC). Epithelial-mesenchymal transition (EMT) is a critical step in tumor progression and transforming growth factor-β1 (TGF-β1) signaling has been shown to play an important role in EMT. In t...

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Bibliographic Details
Main Authors: Lijuan Pang, Qiuxiang Li, Cuilei Wei, Hong Zou, Shugang Li, Weiwei Cao, Jianwei He, Yang Zhou, Xinxin Ju, Jiaojiao Lan, Yutao Wei, Chengyan Wang, Wei Zhao, Jianming Hu, Wei Jia, Yan Qi, Fudong Liu, Jinfang Jiang, Li Li, Jin Zhao, Weihua Liang, Jianxin Xie, Feng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4251902?pdf=render