Micro-Biopsy Forceps in the Assessment of Peritoneal Carcinomatosis: A Possible New Indication?

Peritoneal carcinomatosis (PC) is defined as a metastatic involvement of the peritoneum by several other primary sites and it is characterized by a marked worsening of prognosis, with limited treatment opportunities. Subsequently, PC should be ruled out before any invasive treatment is administered....

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Bibliographic Details
Main Authors: Cecilia Binda, Emanuele Dabizzi, Emanuele Sinagra, Adele Fornelli, Luca Saragoni, Vincenzo Cennamo, Andrea Anderloni, Carlo Fabbri
Format: Article
Language:English
Published: Hoon Jai Chun 2021-07-01
Series:Clinical Endoscopy
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Online Access:http://www.e-ce.org/upload/pdf/ce-2020-241.pdf
Description
Summary:Peritoneal carcinomatosis (PC) is defined as a metastatic involvement of the peritoneum by several other primary sites and it is characterized by a marked worsening of prognosis, with limited treatment opportunities. Subsequently, PC should be ruled out before any invasive treatment is administered. A new through-the-needle micro-biopsy forceps (MF) was recently introduced that permits micro-histology cores. In this case series, we evaluated the feasibility of MF in the assessment of PC to complete patient diagnostic work-ups. Five consecutive patients referred for endoscopic ultrasound staging were sampled using MF. Sampling was feasible in all patients with a technical success of 100%. No adverse events were reported in any cases. This technique was feasible and safe with a technical success rate of 100%. It permitted sampling of peritoneal irregularity, obtained high-quality tissue fragments in all cases, and enabled an additional assessment, i.e., immunohistochemical staining.
ISSN:2234-2400
2234-2443