MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica

MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica

Abstract Background Dendritic cells (DCs) are specialized first-line sensors of foreign materials invading the organism. These sentinel cells rely on pattern recognition receptors such as Nod-like or Toll-like receptors (TLRs) to launch immune reactions against pathogens, but also to mediate toleran...

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Bibliographic Details
Main Authors: Hans Christian Winkler, Julian Kornprobst, Peter Wick, Lea Maria von Moos, Ioannis Trantakis, Elisabeth Maria Schraner, Barbara Bathke, Hubertus Hochrein, Mark Suter, Hanspeter Naegeli
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Particle and Fibre Toxicology
Subjects:
E 551
Food additive
Food toxicology
Gut-associated lymphoid tissue
Inflammatory bowel disease
Nanomaterial
Online Access:http://link.springer.com/article/10.1186/s12989-017-0202-8

Internet

http://link.springer.com/article/10.1186/s12989-017-0202-8

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