Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration

Neurodegenerative diseases, including Huntington’s disease (HD) and Alzheimer's disease (AD), are progressive conditions characterized by selective, disease-dependent loss of neuronal regions and/or subpopulations. Neuronal loss is preceded by a long period of neuronal dysfunction, during which...

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Bibliographic Details
Main Authors: Rafael Alcalà-Vida, Ali Awada, Anne-Laurence Boutillier, Karine Merienne
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304307