The physiological role of Motin family and its dysregulation in tumorigenesis

The physiological role of Motin family and its dysregulation in tumorigenesis

Abstract Members in Motin family, or Angiomotins (AMOTs), are adaptor proteins that localize in the membranous, cytoplasmic or nuclear fraction in a cell context-dependent manner. They control the bioprocesses such as migration, tight junction formation, cell polarity, and angiogenesis. Emerging evi...

Full description

Bibliographic Details
Main Authors: Tingting Huang, Yuhang Zhou, Jinglin Zhang, Alfred S. L. Cheng, Jun Yu, Ka Fai To, Wei Kang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Translational Medicine
Subjects:
AMOT
AMOTL1
AMOTL2
Hippo pathway
YAP1
Cancer
Online Access:http://link.springer.com/article/10.1186/s12967-018-1466-y

Internet

http://link.springer.com/article/10.1186/s12967-018-1466-y

Similar Items