Nicotinamide Phosphoribosyltransferase Knockdown Leads To Lipid Accumulation In HepG2 Cells Through The SIRT1-AMPK Pathway

Nicotinamide Phosphoribosyltransferase Knockdown Leads To Lipid Accumulation In HepG2 Cells Through The SIRT1-AMPK Pathway

Objective Nicotinamide phosphoribosyltransferase (NAMPT), which is responsible for biosynthesis of nicotinamide adenine dinucleotide (NAD), has a regulatory role in cellular metabolism and thus, might be implicated in non-alcoholic fatty liver disease (NAFLD). This study aimed to show how NAMPT dow...

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Bibliographic Details
Main Authors: Davod Ilbeigi, Mitra Nourbakhsh, Parvin Pasalar
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-09-01
Series:Cell Journal
Subjects:
acetyl-coa carboxylase
nicotinamide phosphoribosyltransferase
non-alcoholic fatty liver disease
sirtiun 1
sterol regulatory element-binding protein-1c
Online Access:https://celljournal.org/journal/article/fulltext/nicotinamide-phosphoribosyltransferase-nampt-knockdown-contributes-to-the-development-of-fatty-liver-disease-through-the-sirt1-ampk-pathway.pdf

Internet

https://celljournal.org/journal/article/fulltext/nicotinamide-phosphoribosyltransferase-nampt-knockdown-contributes-to-the-development-of-fatty-liver-disease-through-the-sirt1-ampk-pathway.pdf

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