A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial

Abstract Background Depressive symptoms are usually managed within primary care and antidepressant medication constitutes the first-line treatment. It remains unclear at present which people are more likely to benefit from antidepressant medication. This paper describes the protocol for a randomised...

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Main Authors: George Salaminios, Larisa Duffy, Anthony Ades, Ricardo Araya, Katherine S. Button, Rachel Churchill, Tim Croudace, Catherine Derrick, Padraig Dixon, Christopher Dowrick, Simon Gilbody, William Hollingworth, Vivien Jones, Tony Kendrick, David Kessler, Daphne Kounali, Paul Lanham, Alice Malpass, Tim J. Peters, Derek Riozzie, Jude Robinson, Debbie Sharp, Laura Thomas, Nicky J. Welton, Nicola Wiles, Glyn Lewis
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-017-2253-4