Ground Calcium Carbonate as a Low Cost and Biosafety Excipient for Solubility and Dissolution Improvement of Praziquantel

Ground Calcium Carbonate as a Low Cost and Biosafety Excipient for Solubility and Dissolution Improvement of Praziquantel

Calcium carbonate is an abundant mineral with several advantages to be a successful carrier to improve oral bioavailability of poorly water-soluble drugs, such as praziquantel. Praziquantel is an antiparasitic drug classified in group II of the Biopharmaceutical Classification System hence character...

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Bibliographic Details
Main Authors:	Ana Borrego-Sánchez, Rita Sánchez-Espejo, Beatrice Albertini, Nadia Passerini, Pilar Cerezo, César Viseras, C. Ignacio Sainz-Díaz
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Pharmaceutics
Subjects:	praziquantel calcium carbonate schistosomiasis bioavailability solubility cytotoxicity
Online Access:	https://www.mdpi.com/1999-4923/11/10/533

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